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Influence of Different Zn Substitution Sites on the Crystallinity and Morphology of Zn-Doped Nano-Hydroxyapatite Powder
Yangyang Wang, Tao Wang
College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Yudao Street 29, Nanjing 210016, China
received October 16, 2020, received in revised form February 17, 2021, accepted March 16, 2021
Vol. 12, No. 2, Pages 81-86 DOI: 10.4416/JCST2020-00023
Abstract
Zn-substituted hydroxyapatite (ZnHA) has been studied as a biomaterial with enhanced biological activity, which is related to its crystal structure and micromorphology. We investigated the inner contacts at the sites of Zn-substitution, crystal structure conversion behavior and variation of morphology in ZnHA. The composition of samples with different Zn/(Zn+Ca) molar ratios (0 mol%, 1 mol%, 5 mol%, 10 mol% and 20 mol%) was characterized by means of X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR). The morphologies of samples were examined with scanning electron microscopy (SEM) and high-resolution transmission electron microscopy (HRTEM). The Zn2+ ion distribution was analyzed by means of X-ray photoelectron spectroscopy (XPS). From the XRD and FTIR data, it could be observed that the crystallinity of the precipitates decreased with increasing content of Zn2+ ions, with the formation of amorphous phase when the concentration of Zn2+ ions exceeded 10 mol%. SEM and HRTEM results showed that the morphologies changed from nano-needle clusters to nanospheres with increasing concentration of Zn2+ ions. According to the XPS results, at low Zn concentrations (0 – 5 mol% Zn), the Zn2+ ions only occupied the Ca(II) sites. However, with the increase in the concentration of Zn2+ ions, Zn2+ ions also gradually occupied the Ca(I) sites. Hence, we can conclude that the change in morphology and crystal structure is affected by the Zn2+ ions occupying the different Ca2+ ions sites.
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Keywords
Zn-doped, hydroxyapatite, morphology, crystal structure, substituted sites
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