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The Role of Bioinorganics in Improving the Mechanical Properties of Silicate Ceramics as Bone Regenerative Materials
H. Mohammadi1, M. Sepantafar2,3, A. Ostadrahimi4
1 Department of Biomaterials, Science and Research Branch, Islamic Azad University, Yazd, Iran
2 Department of Stem Cell and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
3 Department of Metallurgy and Materials Engineering, Faculty of Engineering, University of Semnan, Semnan, Iran
4 Department of Biomaterials, Science and Research Branch, Islamic Azad University, Tehran, Iran
received October 9, 2014, received in revised form January 4, 2015, accepted January 23, 2015
Vol. 6, No. 1, Pages 1-8 DOI: 10.4416/JCST2014-00043
Abstract
One of the important parameters in bone regeneration is the mechanical properties. The calcium-silicate-based ceramics (Ca-Si) have shown great potential as orthopedic biomaterials, however, they are brittle. The addition of trace elements such as magnesium (Mg2+) or zinc (Zn2+) to the silicate biomaterials has been used to overcome this complication. In this review paper, we investigate the effects of adding different trace elements to improve the mechanical properties of silicate-based ceramics as bone regenerative materials.
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Keywords
Calcium silicate, mechanical properties, trace element, bone regeneration
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