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In Vitro Characterization of Carbon-Nanotube-Reinforced Hydroxyapatite Composite Coating on 316L Stainless Steel
S.P. Mohamadi1, A. Nemati1, Z. Sadeghian2
1 Department of Materials Science and Engineering, Sharif University of Technology, Azadi street, P. O. Box 11155 – 4363 Tehran, Iran
2 Research Institute of Petroleum Industry (RIPI), West Blvd. Azadi sport complex, P.O. Box 14857 – 3311, Tehran, Iran
received March 26, 2013, received in revised form June 12, 2013, accepted August 21, 2013
Vol. 4, No. 3, Pages 163-168 DOI: 10.4416/JCST2013-00009
Abstract
This investigation focused on a comparison between hydroxyapatite (HA) and carbon-nanotube-reinforced hydroxyapatite composite (CNTs/HA) coatings. The HA and CNTs/HA composite (with 5 wt% CNTs) coatings were prepared with the sol-gel method on 316L stainless steel. Phase evaluation by means of XRD and Raman spectroscopy was performed on the HA and CNTs/HA composite coatings. The coatings were immersed in simulated body fluid (SBF) in order to evaluate the biological properties of the coatings. During the first week of immersion, the increase in the amount of Ca2+ precipitation in the SBF when CNTs/HA was used was lower than for the HA coatings. This behavior can be related to the difference in the amount of amorphous phases in the two types of coatings. The microstructure of the coatings was studied with AFM and SEM. The results showed that the crystallinity of the composite coating is greater than that of the HA coatings.
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Keywords
Keywords: hydroxyapatite, carbon nanotube, nanocomposite, bioactivity, in vitro test
References
1 Hench, L.L.: Bioceramics: from concept to clinic, J. Am. Ceram. Soc., 74, 487 – 510, (1991).
2 Jarcho, M.: Calcium phosphate ceramics as hard tissue prosthetics, Clin. Orthop. Relat. R., 157, 59 – 78, (1981).
3 Gu, Y.W., Khor, K.A., Pan, D., Cheang, P.: Activity of plasma sprayed yttria stabilized zirconia reinforced hydroxyapatite/Ti-6Al-4V composite coatings in simulated body fluid, Biomaterials, 25, 77 – 85, (2004).
4 Evis, Z., Doremus, R.H.: Coatings of hydroxyapatite-nanosize alpha alumina composites on Ti-6Al-4V, Mater. Lett., 59, 3824 – 7, (2005).
5 White, A.A., Best, S.M., Kinloch, I.A.: Hydroxyapatite-carbon nanotube composites for biomedical applications: a review, Int. J. Appl. Ceram. Tech., 4, (1), 1 – 13, (2007).
6 Lahiri, D., Ghosh, S., Agarwal, A.: Carbon nanotube reinforced hydroxyapatite composite for orthopedic application: A review, Mat. Sci. Eng. C, 32, 1727 – 1758, (2012).
7 Hahn B.D., Lee, J.M., Park, D.S.: Mechanical and in vitro biological performances of hydroxyapatite-carbon nanotube composite coatings deposited on Ti by aerosol deposition, Acta Biomater., 5, 3205 – 3214, (2009).
8 Jackson, J., Ahmed, W.: Applications of Carbon Nanotubes in Bio-Nanotechnology, in Surface Engineered Surgical Tools and Medical Devices, Eds. Springer Science+Business Media LLC, New York, NY, USA, pp. 439 – 475, 2007.
9 Najafi, H., Nemati, A., Sadeghian, Z.: Inclusion of carbon nanotubes in a hydroxyapatite sol-gel matrix, Ceram. Int., 35, 2987 – 2991, (2009).
10 Spanos, N., Misirlis, D.Y., Kanellopoulou, D.G., Koutsoukos. P.G.: Seeded growth of hydroxyapatite in simulated body fluid, J. Mater. Sci., 41, 1805 – 1812, (2006).
11 Chen, Y., Zhang, Y.Q., Zhang, T.H., Gan, C.H., Zheng, C.Y., Yu, G.: Carbon nanotube reinforced hydroxyapatite composite coatings produced through laser surface alloying, Carbon, 44, 37 – 45, (2006).
12 Kealley, C., Elcombe, M., Riessen, A.V., Ben-Nissan., B.: Development of carbon nanotube-reinforced hydroxyapatite bioceramics, Physica B, 385 – 386, 496 – 498, (2006).
13 Kaya, C.: Electrophoretic deposition of carbon nanotube-reinforced hydroxyapatite bioactive layers on Ti-6Al-4V alloys for biomedical applications, Ceram. Int., 34, 1843 – 1847, (2007).
14 Balani, K., Anderson, R., Laha, T., Andara. M.: Plasma-sprayed carbon nanotube reinforced hydroxyapatite coatings and their interaction with human osteoblasts in vitro, Biomaterials, 28, 618 – 624, (2007).
15 Li, A., Sun, K., Dong, W., Zhao, D.: Mechanical properties, microstructure and histocompatibility of MWCNTs/HAp biocomposites, Mater. Lett., 61, 1839 – 1844, (2007).
16 Bhattarai, S.R., Aryal, S.: Carbon nanotube-hydroxyapatite nanocomposite for DNA complexation, Mat. Sci. Eng. C, 28, 64 – 69 (2008).
17 Weng, J., Liu, Q., Wolke, J.G.C., Zhang, X., de Groot, K.: Forming and characteristics of the apatite layer on plasma sprayed hydroxyapatite-coatings in simulated body fluid, Biomaterials, 18, 1027 – 1035, (1997).
18 Park, J.-H., Lee, D.Y., Oh, K.T., Lee, Y.K.: Bioactivity of calcium phosphate coatings prepared by electrodeposition in a modified simulated body fluid, Mater. Lett., 60, 2573 – 2577, (2006).
19 Zhang, Q., Leng, Y., Xin, R., Wang, C., Lu, X., Chen, J.: An effective approach to activate 316L stainless steel for biomimetic coating of calcium phosphate, J. Mater. Sci., 42, 6205 – 6211, (2007).
20 Wang, Y., Sam, Z., Zeng, X., Cheng, K., Qian, M., Weng, W.: In vitro behavior of fluoridated hydroxyapatite coatings in organic-containing simulated body fluid, Mater. Sci. Eng. C, 27, 244 – 250, (2007).
21 Kokubo, T., Takadama. H.: How useful is SBF in predicting in vivo bone bioactivity?, Biomaterials, 27, 2907 – 2915, (2006).
22 Xu, J.L., Khor, K.A., Sui, J.J., Chen, W.N.: Preparation and characterization of a novel hydroxyapatite/carbon nanotubes composite and its interaction with osteoblast-like cells, Mater. Sci. Eng. C, 29, 44 – 49, (2009).
23 Sadeghian, Z.: Large scale production of multi-walled carbon nanotubes by low-cast spray pyrolysis of hexane, New Carbon Mater., 24, 33 – 37, (2009).
24 Guo, Y., Yao, Y.B., Ning, C.Q., Chu, L.F., Guo, Y.J.: Fabrication of mesoporous carbonated hydroxyapatite/carbon nanotube composite coatings by microwave irradiation method, Mater. Lett., 65, 1007 – 1009, (2011).
25 Li, P., Yang, Q., Zhang, F., Kokubo, T.: The effect of residual glassy phase in a bioactive glass-ceramic on the formation of its surface apatite layer in vitro, J. Mater. Sci: Mater. M., 3, 452 – 456, (1992).
26 Rath, P.C., Singh, B.P., Besra, L., Bhattacharjee S.: Multiwalled carbon nanotubes reinforced hydroxyapatite-chitosan composite coating on Ti metal: Corrosion and mechanical properties, J. Am. Ceram. Soc., 95, [9], 2725 – 2731, (2012).
27 Kweh, S.W.K., Khor, K.A., Cheang, P.: An in vitro investigation of plasma sprayed hydroxyapatite (HA) coatings produced with flame-spheroidized feedstock, Biomaterials, 23, 775 – 785, (2002).
28 Grassmann, O., Heimann, R.B.: Compositional and microstructural changes of engineered plasma sprayed hydroxyapatite coatings on Ti-6Al-4V substrates during incubation in protein-free simulated body fluid, J. Biomed Mater. Res., 53, 685 – 693, (2000).
29 Luo, Z.S., Cui, F.Z., Feng, Q.L., Li, H.D., Zhu, X.D., Spector, M.: In vitro and in vivo evaluation of degradability of hydroxyapatite coatings synthesized by ion beam-assisted deposition, Surf. Coat. Tech., 131, 192 – 195, (2000).
30 Wang, Y., Zhang, S., Cheng, K., Qian, M., Weng, W.: In vitro behavior of fluoridated hydroxyapatite coatings in organic-containing simulated body fluid, Mater. Sci. Eng. C, 27, 244 – 250, (2007).
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