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Effect of Heat Treatment on Grain Growth of Nanocrystalline Hydroxyapatite Powder

I. Mobasherpour, E. Salahi

Materials and Energy Research Center, Ceramics Department, P.O. Box 31787-316, Karaj, Iran

received December 8, 2010, received in revised form February 23, 2011, accepted March 4, 2011

Vol.2, No.2, Pages 119-124   DOI: 10.4416/JCST2010-00046

Abstract

Nanocrystalline hydroxyapatite powder was synthesized with the solution-precipitation method followed by heat treatment in order to evolve phases, which were studied with XRD and TEM techniques. The crystallites sizes were estimated with the Scherrer method and results confirmed with TEM micrographs. The experimental observations showed that nanocrystalline hydroxyapatite can be successfully prepared from raw materials with the precipitation technique. Compared to other techniques, the precipitation technique is a competitive method for nanocrystalline hydroxyapatite synthesis. Moreover, a growth kinetic investigation was performed on the nanocrystalline growth process during heat treatment. Results have shown that grain sizes increase exponentially with temperature and the growth rate constants increase with time. The average activation energy of hydroxyapatite grain growth obtained 30.33 – 77.78 KJ/mol with this method.

Keywords

Hydroxyapatite, nanostructures, crystal growth, electron microscopy, X-ray diffraction

References

¹ Suchanek, W., Yoshimura, M.: Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants, J. Mater. Res., 13, [1], (1998).

² Hench, L.L.: Bioceramics: from concept to clinic, J. Am. Ceram. Soc., 74, 1487, (1991).

³ Pontier, C., Viana, M., Champion, E., Chulia, D.: Apatitic calcium phosphates used in compression: rationalization of the end-use properties, Powder Technology, 130, 436, (2003).

⁴ He, Z., Ma, J., Wang, C.: Constitutive modeling of the densification and the grain growth of hydroxyapatite ceramics, Biomaterials, 26, 1613, (2005).

⁵ Ramesh, S., Tan, C.Y., Bhaduri, S.B., Teng, W.D.: Rapid densification of nanocrystalline hydroxyapatite for biomedical applications, Ceram. Int., 33, 1363, (2007).

⁶ Kokubo, T., Kim, H.M., Kawashita, M.: Novel bioactive materials with different mechanical properties, Biomaterials, 24, 2161, (2003).

⁷ Gibson, I.R., Ke, S., Best, S.M., Bonfield, W.: Effect of powder characteristics on the sinterability of hydroxyapatite powders, J.Mater.Sci.Mater.M., 12, 163, (2001).

⁸ Aoki, H.: Science and Medical Applications of Hydroxyapatite, JAAS Tokyo, (1991).

⁹ LeGeros, R.Z.: Calcium Phosphate in Oral Biology and Medicine, Karger AG, (1991).

¹⁰ Best, S., Bonfield, W.: Processing behaviour of hydroxyapatite powders with contrasting morphology, J. Mater. Sci.: Mater. M., 5, 516, (1994).

¹¹ Legeros, R.Z.: Biodegradation and bioresorption of calcium phosphate ceramics, Clin. Mater, 14, 65, (1993).

¹² Yeong, K.C.B., Wang, J., Ng, S.C.: Fabricating densified hydroxyapatite ceramics from a precipitated precursor, Mater. Lett., 38, 208, (1999).

¹³ Stupp, S.I., Ciegler, G.W.: Organoapatites: Materials for artificial bone. I. Synthesis and microstructure, J. Biomed. Mater. Res., 26, 169, (1992).

¹⁴ Webster, T.J., Ergun, C., Doremus, R.H., Siegel, R.W., Bizios, R.: Enhanced osteoclast-like cell functions on nanophase ceramics, Biomaterials, 22, 1327, (2001).

¹⁵ Webster, T.J., Siegel, R.W., Bizios, R.: Osteoblast adhesion on nanophase ceramics, Biomaterials, 20, 1221, (1999).

¹⁶ Han, Y., Li, S., Wang, X., Chen, X.: Synthesis and sintering of nanocrystalline hydroxyapatite powders by citric acid sol-gel combustion method, Mater. Res. Bull., 39, 25-32, (2004).

¹⁷ Mobasherpour, I., Soulati Heshajin, M., Kazemzadeh, A., Zakeri, M.: Synthesis of nanocrystalline hydroxyapatite by using precipitation method, J. Alloy. Compd., 430, 330, (2007).

¹⁸ Cullity, B.D.: Elements of X-ray Diffraction, Second ed., Addison-Wesley Publishing, (1977).

¹⁹ Williamson, G.K., Hall, W.H.: X-ray line broadening from filed aluminium and wolfram, Acta Metall., 1, 22-31, (1953).

²⁰ Zakeri, M., Yazdani-Rad, R., Enayati, M.H., Rahimipour, M.R.: Synthesis of nanocrystalline MoSi₂ by mechanical alloying, J. Alloy. Compd., 403, 258, (2005).

²¹ Atkinson, H.V.: Overview no. 65: Theories of normal grain growth in pure single phase systems, Acta Metall., 36, 469, (1988).

²² Liu, F., Kirchheim, R.: Comparison between kinetic and thermodynamic effects on grain growth, Thin Solid Films, 466, 108, (2004).

²³ Höfler, H.J., Tao, R., Kim, L., Averback, R.S., Altetetter, C.J.: Mechanical properties of single-phase and nano-compo­site metals and ceramics, Nanostruct. Mater., 6, 901, (1995).

²⁴ Liu, F., Kirchheim, R.: Nano-scale grain growth inhibited by reducing grain boundary energy through solute segregation, J. Cryst. Growth, 264, 385, (2004).

Copyright

Göller Verlag GmbH

Acknowledgments

This work was supported by the Materials and Energy Research Center. The authors would also like to thank Dr. B. Jadedeyan for her help in improving the English of this paper.